Bracketology by Jonathon Warriner
Updated February 15th, 2021
| West Region | South Region |
| 1.Gonzaga | 1.Baylor |
| 16.Prairie View A&M/ Texas State | 16.South Dakota/ North Carolina A&T |
| 8.Louisville | 8.LSU |
| 9.Oregon | 9.Minnesota |
| 4.Tennessee | 4.Creighton |
| 13.Wright State | 13.UC Santa Barbara |
| 5.Wisconsin | 5.Missouri |
| 12.Western Kentucky | 12.Toledo |
| 3.Villanova | 3.Iowa |
| 14.Vermont | 14.Liberty |
| 6.Purdue | 6.Clemson |
| 11.VCU | 11.Colorado State |
| 2.Oklahoma | 2.Illinois |
| 15.Colgate | 15.Grand Canyon |
| 7.BYU | 7.Oklahoma State |
| 10.UCLA | 10.Saint Bonaventure |
| East Region | Midwest Region |
| 1.Ohio State | 1.Michigan |
| 16.Bryant | 16.Eastern Washington |
| 8.Colorado | 8.Arkansas |
| 9.Seton Hall | 9.North Carolina |
| 4.Texas Tech | 4.Texas |
| 13.Belmont | 13.Winthrop |
| 5.Florida State | 5.USC |
| 12.Utah State/ Stanford | 12.Drake |
| 3.West Virginia | 3.Virginia |
| 14.Abilene Christian | 14.UNC Greensboro |
| 6.Virginia Tech | 6.Kansas |
| 11.Loyola-Chicago | 11.Uconn/ Indiana |
| 2.Alabama | 2.Houston |
| 15.Siena | 15.Northeastern |
| 7.Rutgers | 7.Xavier |
| 10.Boise State | 10.Florida |
NIT One Seeds: San Diego State, Ole Miss, Maryland, Saint Louis
The Next Five: Richmond, Saint John’s, Syracuse, Memphis, Wichita State