Bracketology by Jonathon Warriner
Updated January 21st, 2021
| West Region | South Region |
| 1.Gonzaga | 1.Baylor |
| 16.Alabama A&M/ North Dakota State | 16.Colgate/ North Carolina A&T |
| 8.Oregon | 8.USC |
| 9.Louisville | 9.Seton Hal |
| 4.Ohio State | 4.Illinois |
| 13.Abilene Christian | 13.Western Kentucky |
| 5.Texas Tech | 5.Virginia |
| 12.Richmond/ San Diego State | 12.Furman |
| 3.Wisconsin | 3.Minneosta |
| 14.Bryant | 14.Siena |
| 6.West Virginia | 6.Boise State |
| 11.Florida | 11.Wichita State |
| 2.Houston | 2.Alabama |
| 15.Cal State Bakersfield | 15.Vermont |
| 7.Clemson | 7.Creighton |
| 10.LSU | 10.Pittsburgh |
| Midwest Region | East Region |
| 1.Texas | 1.Iowa |
| 16.Texas State | 16.Eastern Washington |
| 8.BYU | 8.Uconn |
| 9.Drake | 9.Oklahoma |
| 4.Missouri | 4.Oklahoma State |
| 13.Liberty | 13.Toledo |
| 5.Purdue | 5.UCLA |
| 12.Winthrop | 12.Indiana/ Arkansas |
| 3.Tennessee | 3.Kansas |
| 14.Wright State | 14.Belmont |
| 6.Florida State | 6.Colorado |
| 11.Utah State | 11.North Carolina |
| 2.Michigan | 2.Villanova |
| 15.Northeastern | 15.Grand Canyon |
| 7.Virginia Tech | 7.Saint Louis |
| 10.Xavier | 10.Rutgers |
NIT One Seeds: Maryland, Marquette, Stanford, Providence
The Next Five: Michigan State, NC State, St. Bonaventure, Georgia Tech, Syracuse