Bracketology by Jonathon Warriner
Updated February 22nd, 2021
| West Region | South Region |
| 1.Gonzaga | 1.Baylor |
| 16.Prairie View A&M/ Texas State | 16.South Dakota/ North Carolina A&T |
| 8.Colorado | 8.Rutgers |
| 9.Boise State | 9.Oregon |
| 4.Kansas | 4.Creighton |
| 13.Toledo | 13.UC Santa Barbara |
| 5.Virginia Tech | 5.Tennessee |
| 12.Belmont | 12.Western Kentucky |
| 3.Iowa | 3.Houston |
| 14.Vermont | 14.Liberty |
| 6.Clemson | 6.Arkansas |
| 11.Saint Bonaventure | 11.Drake |
| 2.Oklahoma | 2.Illinois |
| 15.UNC Greensboro | 15.Grand Canyon |
| 7.Purdue | 7.Oklahoma State |
| 10.San Diego State | 10.VCU |
| East Region | Midwest Region |
| 1.Ohio State | 1.Michigan |
| 16.Bryant | 16.James Madison |
| 8.Florida | 8.North Carolina |
| 9.Loyola-Chicago | 9.UCLA |
| 4.Texas Tech | 4.Virginia |
| 13.Wright State | 13.Winthrop |
| 5.USC | 5.Texas |
| 12.Seton Hall/ Wichita State | 12.UConn/ Minnesota |
| 3.Florida State | 3.West Virginia |
| 14.Abilene Christian | 14.Navy |
| 6.Wisconsin | 6.Missouri |
| 11.Colorado State | 11.Louisville |
| 2.Alabama | 2.Villanova |
| 15.Siena | 15.Eastern Washington |
| 7.LSU | 7.BYU |
| 10.Xavier | 10.Maryland |
NIT One Seeds: Indiana, Utah State, Syracuse, Stanford
The Next Five: Saint John’s, Ole Miss, Duke, Saint Louis, SMU