Bracketology by Jonathon Warriner
Updated January 26th, 2021
| West Region | South Region |
| 1.Gonzaga | 1.Baylor |
| 16.Alabama A&M/ North Dakota State | 16.Colgate/ North Carolina A&T |
| 8.Virginia Tech | 8.Louisville |
| 9.Oregon | 9.Drake |
| 4.Kansas | 4.Wisconsin |
| 13.Abilene Christian | 13.Furman |
| 5.Purdue | 5.Florida State |
| 12.Winthrop | 12.Western Kentucky |
| 3.Illinois | 3.Ohio State |
| 14.Bryant | 14.Siena |
| 6.Oklahoma State | 6.Colorado |
| 11.Pittsburgh/ Wichita State | 11.LSU |
| 2.Houston | 2.Alabama |
| 15.Cal State Bakersfield | 15.Vermont |
| 7.USC | 7.BYU |
| 10.Florida | 10.Xavier |
| Midwest Region | East Region |
| 1.Texas | 1.Michigan |
| 16.Eastern Washington | 16.Texas State |
| 8.UCLA | 8.Clemson |
| 9.Rutgers | 9.Uconn |
| 4.Creighton | 4.Tennessee |
| 13.Toledo | 13.Liberty |
| 5.Virginia | 5.Texas Tech |
| 12.Wichita State/ Arkansas | 12.Indiana |
| 3.Missouri | 3.West Virginia |
| 14.Belmont | 14.Wright State |
| 6.Boise State | 6.Minnesota |
| 11.Maryland | 11.Stanford |
| 2.Iowa | 2.Villanova |
| 15.Grand Canyon | 15.Northeastern |
| 7.Oklahoma | 7.Saint Louis |
| 10.Seton Hall | 10.North Carolina |
NIT One Seeds: Michigan State, Saint Bonaventure, Loyola-Chicago, Georgia Tech
The Next Five: VCU, Providence, Utah State, Colorado State, SMU