Bracketology by Jonathon Warriner
Updated January 31st, 2022
| South Region (San Antonio) | Midwest Region (Chicago) |
| 1.Auburn (Greenville) | 1.Baylor (Fort Worth) |
| 16.Liberty/ Longwood | 16.Southern/ Texas A&M CC |
| 8.Murray State | 8.Indiana |
| 9.Davidson | 9.Seton Hall |
| 4.Michigan State (Pittsburgh) | 4.Alabama (Buffalo) |
| 13.UAB | 13.Ohio |
| 5.Xavier | 5.Houston |
| 12.Florida/ San Diego State | 12.Chattanooga |
| 3.UCLA (San Diego) | 3.Villanova (Pittsburgh) |
| 14.Seattle | 14.Vermont |
| 6.Ohio State | 6.Tennessee |
| 11.North Carolina | 11.Oregon |
| 2.Kansas (Milwaukee) | 2.Wisconsin (Milwaukee) |
| 15.Arkansas State | 15.UNC Wilmington |
| 7.St. Mary’s | 7.USC |
| 10.Arkansas | 10.Oklahoma |
| East Region (Philadelphia) | West Region (San Francisco) |
| 1.Purdue (Indianapolis) | 1.Gonzaga (Portland) |
| 16.Navy | 16.Cal State Fullerton |
| 8.TCU | 8.Iowa |
| 9.Miami | 9.Colorado State |
| 4.Providence (Buffalo) | 4.LSU (Portland) |
| 13.Oakland | 13.South Dakota State |
| 5.Iowa State | 5.Marquette |
| 12.Iona | 12.Wyoming/ San Francisco |
| 3.Duke (Greenville) | 3.Texas Tech (Fort Worth) |
| 14.Princeton | 14.Wagner |
| 6.UConn | 6.Illinois |
| 11.West Virginia | 11.Loyola-Chicago |
| 2.Kentucky (Indianapolis) | 2.Arizona (San Diego) |
| 15.Norfolk State | 15.Weber State |
| 7.Texas | 7.Boise State |
| 10.Wake Forest | 10.BYU |
NIT One Seeds: Creighton, Stanford, Florida State, VCU
The Next Five: SMU, Mississippi State, Texas A&M, Belmont, Saint Louis