Bracketology by Jonathon Warriner
Updated January 22nd, 2022
| South Region (San Antonio) | Midwest Region (Chicago) |
| 1.Auburn (Greenville) | 1.Baylor (Fort Worth) |
| 16.Winthrop/ Norfolk State | 16.Southeast Louisiana/ Alcorn State |
| 8.Davidson | 8.Colorado State |
| 9.Texas | 9.Creighton |
| 4.Xavier (Portland) | 4.Kentucky (Buffalo) |
| 13.New Mexico State | 13.Oakland |
| 5.UCLA | 5.Ohio State |
| 12.Florida/ Minnesota | 12.Iona |
| 3.Texas Tech (Fort Worth) | 3.Villanova (Pittsburgh) |
| 14.Liberty | 14.Towson |
| 6.USC | 6.Iowa State |
| 11.San Francisco | 11.Wake Forest |
| 2.Wisconsin (Milwaukee) | 2.Purdue (Indianapolis) |
| 15.Princeton | 15.Texas State |
| 7.Murray State | 7.Marquette |
| 10.San Diego State | 10.Oregon |
| West Region (San Francisco) | East Region (Philadelphia) |
| 1.Gonzaga (Portland) | 1..Kansas (Milwaukee) |
| 16.Weber State | 16.Wagner |
| 8.Indiana | 8.Loyola-Chicago |
| 9.Boise State | 9.Miami |
| 4.Houston (San Diego) | 4.Providence (Buffalo) |
| 13.UAB | 13.Ohio |
| 5.Alabama | 5.Tennessee |
| 12.Florida State/ Saint Mary’s | 12.Chattanooga |
| 3.LSU (Indianapolis) | 3.Michigan State (Pittsburgh) |
| 14.South Dakota State | 14.Vermont |
| 6.Seton Hall | 6.UConn |
| 11.West Virginia | 11.TCU |
| 2.Arizona (San Diego) | 2.Duke (Greenville) |
| 15.Cal State Fullerton | 15.Navy |
| 7.BYU | 7.Illinois |
| 10.Iowa | 10.Oklahoma |
NIT One Seeds: Wyoming, Belmont, Stanford, Mississippi State
The Next Five: Kansas State, North Carolina, Texas A&M, Arkansas, Cincinnati