Bracketology by Jonathon Warriner
Updated January 31st, 2021
| South Region | West Region |
| 1.Baylor | 1.Gonzaga |
| 16.Navy/ North Carolina A&T | 16.Alabama A&M/ South Dakota |
| 8.BYU | 8.Rutgers |
| 9.Colorado | 9.Clemson |
| 4.Wisconsin | 4.Texas Tech |
| 13.Wright State | 13.Furman |
| 5.Florida State | 5.Creighton |
| 12.Winthrop | 12.Western Kentucky |
| 3.Iowa | 3.Missouri |
| 14.Liberty | 14.Bryant |
| 6.USC | 6.Kansas |
| 11.LSU | 11.Maryland |
| 2.Alabama | 2.Ohio State |
| 15.Grand Canyon | 15.Vermont |
| 7.Oklahoma State | 7.Boise State |
| 10.Uconn | 10.Saint Louis |
| East Region | Midwest Region |
| 1.Villanova | 1.Michigan |
| 16.Coastal Carolina | 16.Weber State |
| 8.Minnesota | 8.Xavier |
| 9.North Carolina | 9.Louisville |
| 4.Tennessee | 4.Virginia |
| 13.Toledo | 13.Abilene Christian |
| 5.West Virginia | 5.UCLA |
| 12.San Diego State/ Georgia Tech | 12.Saint Bonaventure/ Arkansas |
| 3.Illinois | 3.Oklahoma |
| 14.Belmont | 14.UC Irvine |
| 6.Florida | 6.Purdue |
| 11.Oregon | 11.Stanford |
| 2.Texas | 2.Houston |
| 15.Siena | 15.Northeastern |
| 7.Virginia Tech | 7.Drake |
| 10.Indiana | 10.Colorado State |
NIT One Seeds: Syracuse, Saint Johns, Seton Hall, Richmond
The Next Five: Wichita State, VCU, Loyola (Ill), Utah State, Memphis