Bracketology by Jonathon Warriner
Updated December 27th, 2020
| West Region | South Region |
| 1.Gonzaga | 1.Baylor |
| 16.Bryant/ Colgate | 16.Texas Southern/ Morgan State |
| 8.Florida State | 8.Syracuse |
| 9.Indiana | 9.SMU |
| 4.Texas Tech | 4.Michigan State |
| 13.Wright State | 13.Vermont |
| 5.Duke | 5.San Diego State |
| 12.Loyola-Chicago | 12.Winthrop |
| 3.West Virginia | 3.Iowa |
| 14.Abeline Christian | 14.Murray State |
| 6.Clemson | 6.Xavier |
| 11.Stanford | 11.Virginia Tech |
| 2.Rutgers | 2.Houston |
| 15.New Mexico State | 15.Furman |
| 7.Ohio State | 7.Michigan |
| 10.Florida | 10.Arkansas |
| East Region | Midwest Region |
| 1.Villanova | 1.Kansas |
| 16.Siena | 16.Montana |
| 8.UCLA | 8.Northwestern |
| 9.NC State | 9.Uconn |
| 4.Missouri | 4.Creighton |
| 13.South Dakota State | 13.Georgia State |
| 5.Minnesota | 5.Louisville |
| 12.Seton Hall/ Colorado | 12.LSU/ Richmond |
| 3.Illinois | 3.Tennessee |
| 14.Ohio | 14.UC Santa Barbara |
| 6.Saint Louis | 6.Virginia |
| 11.Oklahoma | 11.Western Kentucky |
| 2.Texas | 2.Wisconsin |
| 15.Northeastern | 15.Liberty |
| 7.Oregon | 7.North Carolina |
| 10.USC | 10.Oklahoma State |
NIT One Seeds: Ole Miss, Marquette, Dayton, Providence
The Next Five: Boise State, Penn State, Arizona, BYU, TCU