Bracketology by Jonathon Warriner
Updated April 8th, 2022
| East Region (New York City) | South Region (Louisville) |
| 1.North Carolina (Greensboro) | 1.Kentucky (Columbus) |
| 16.Mount St. Mary’s/ Howard | 16.Wright State |
| 8.Texas | 8.Memphis |
| 9.Auburn | 9.Seton Hall |
| 4.Michigan State (Albany) | 4.Dayton (Orlando) |
| 13.Iona | 13.South Dakota State |
| 5.Texas A&M | 5.Oklahoma State |
| 12.Toledo | 12.Drake |
| 3.Villanova (Albany) | 3.Creighton (Denver) |
| 14.Yale | 14.Montana State |
| 6.Ohio State | 6.Colorado State |
| 11.Virginia | 11.Colorado/ Iowa State |
| 2.Baylor (Des Moines) | 2.Duke (Greensboro) |
| 15.Colgate | 15.Vermont |
| 7.Alabama | 7.TCU |
| 10.Wyoming | 10.Illinois |
| Midwest Region (Kansas City) | West Region (Las Vegas) |
| 1.Houston (Birminghan) | 1.Gonzaga (Sacramento) |
| 16.Texas Southern/ Winthrop | 16.Texas A&M CC |
| 8.Purdue | 8.USC |
| 9.Oregon | 9.Saint Louis |
| 4.Arizona (Denver) | 4.Tennessee (Orlando) |
| 13.UC Irvine | 13.UNC Greensboro |
| 5.Texas Tech | 5.Florida State |
| 12.New Mexico State | 12.North Texas |
| 3.Kansas (Des Moines) | 3.Michigan (Columbus) |
| 14.Towson | 14.Jacksonville |
| 6.Xavier | 6.Oklahoma |
| 11.VCU/ Vanderbilt | 11.Mississippi State |
| 2.Arkansas (Birmingham) | 2.UCLA (Sacramento) |
| 15.Louisiana Lafayette | 15.Morehead State |
| 7.UConn | 7.San Diego State |
| 10.Virginia Tech | 10.Marquette |
NIT One Seeds: Louisville, Arizona State, Iowa, St. Mary’s
The Next Five: Loyola-Chicago, Cincinnati, Indiana, Providence, Wisconsin