Bracketology by Jonathon Warriner
Updated January 9th, 2021
| West Region | South Region |
| 1.Gonzaga | 1.Baylor |
| 16.Bryant/ Colgate | 16.Texas Southern/ North Carolina A&T |
| 8.Seton Hall | 8.Uconn |
| 9.LSU | 9.Drake |
| 4.West Virginia | 4.Rutgers |
| 13.Wright State | 13.Furman |
| 5.Minnesota | 5.Saint Louis |
| 12.Western Kentucky | 12.Winthrop |
| 3.Wisconsin | 3.Houston |
| 14.Abilene Christian | 14.Belmont |
| 6.Texas Tech | 6.Oklahoma State |
| 11.Providence | 11.Indiana |
| 2.Michigan | 2.Tennessee |
| 15.UC Irvine | 15.Eastern Washington |
| 7.Virginia Tech | 7.Oregon |
| 10.Florida | 10.Florida State |
| Midwest Region | East Region |
| 1.Texas | 1.Villanova |
| 16.Siena | 16.Stony Brook |
| 8.Arkansas | 8.Oklahoma |
| 9.Ohio State | 9.Syracuse |
| 4.Creighton | 4.Missouri |
| 13.Toledo | 13.Liberty |
| 5.Louisville | 5.Colorado |
| 12.VCU/ Northwestern | 12.NC State/ Purdue |
| 3.Clemson | 3.Illinois |
| 14.Bryant | 14.Abilene Christian |
| 6.Xavier | 6.Alabama |
| 11.USC | 11.San Diego State |
| 2.Iowa | 2.Kansas |
| 15.Grand Canyon | 15.Northeastern |
| 7.Boise State | 7.Stanford |
| 10.North Carolina | 10.Virginia |
NIT One Seeds: Michigan State, Marquette, Duke, UCLA
The Next Five: Pittsburgh, Maryland, BYU, SMU, Richmond