Bracketology by Jonathon Warriner
Updated March 10th, 2021
| West Region | South Region |
| 1.Gonzaga | 1.Baylor |
| 16.Appalachain State/ Norfolk State | 16.Oral Roberts |
| 8.Uconn | 8.Loyola-Chicago |
| 9.Wisconsin | 9.Rutgers |
| 4.Purdue | 4.Virginia |
| 13.Liberty | 13.Toledo |
| 5.Florida State | 5.Tennessee |
| 12.Winthrop | 12.Ole Miss/ Xavier |
| 3.Oklahoma State | 3.Arkansas |
| 14.UNC Greensboro | 14.Morehead State |
| 6.Clemson | 6.USC |
| 11.Wichita State | 11.Georgia Tech |
| 2.Ohio State | 2.Iowa |
| 15.Cleveland State | 15.Siena |
| 7.Oregon | 7.LSU |
| 10.North Carolina | 10.VCU |
| East Region | Midwest Region |
| 1.Illinois | 1.Michigan |
| 16.Prairie View A&M/ Mount Saint Mary’s | 16.Hartford |
| 8.Florida | 8.Virginia Tech |
| 9.San Diego State | 9.Saint Bonaventure |
| 4.Texas | 4.Villanova |
| 13.UC Santa Barbara | 13.Colgate |
| 5.Creighton | 5.Texas Tech |
| 12.Western Kentucky | 12.Colorado State/ Drake |
| 3.West Virginia | 3.Kansas |
| 14.Grand Canyon | 14.Abeline Christian |
| 6.BYU | 6.Colorado |
| 11.Maryland | 11.Louisville |
| 2.Alabama | 2.Houston |
| 15.Drexel | 15.Eastern Washington |
| 7.Oklahoma | 7.Missouri |
| 10.Michigan State | 10.UCLA |
NIT One Seeds: Boise State, Saint Louis, Syracuse, Seton Hall
Others Considered: Saint John’s, Utah State, SMU, NC State