Bracketology by Jonathon Warriner
Updated March 5th, 2021
| West Region | South Region |
| 1.Gonzaga | 1.Baylor |
| 16.Prairie View A&M/ Norfolk State | 16.South Dakota/ Texas State |
| 8.Virginia Tech | 8.LSU |
| 9.Loyola-Chicago | 9.Maryland |
| 4.Texas | 4.Purdue |
| 13.Toledo | 13.UC Santa Barbara |
| 5.Virginia | 5.Creighton |
| 12.Seton Hall/ Drake | 12.Winthrop |
| 3.Kansas | 3.Houston |
| 14.Vermont | 14.Liberty |
| 6.Tennessee | 6.Clemson |
| 11.Xavier | 11.Rutgers |
| 2.Iowa | 2.Ohio State |
| 15.James Madison | 15.Grand Canyon |
| 7.Oregon | 7.Oklahoma |
| 10.Louisville | 10.VCU |
| East Region | Midwest Region |
| 1.Illinois | 1.Michigan |
| 16.Bryant | 16.Cleveland State |
| 8.Florida | 8.San Diego State |
| 9.UCLA | 9.North Carolina |
| 4.Oklahoma State | 4.Arkansas |
| 13.Navy | 13.Belmont |
| 5.BYU | 5.Texas Tech |
| 12.Colorado State/ Syracuse | 12.Western Kentucky |
| 3.Florida State | 3.Villanova |
| 14.Abilene Christian | 14.UNC Greensboro |
| 6.Colorado | 6.USC |
| 11.Georgia Tech | 11.Saint Bonaventure |
| 2.Alabama | 2.West Virginia |
| 15.Siena | 15.Eastern Washington |
| 7.Missouri | 7.Wisconsin |
| 10.UConn | 10.Wichita State |
NIT One Seeds: Utah State, Michigan State, Duke, Boise State
The Next Five: Saint Louis, Ole Miss, Indiana, Saint John’s, Providence