Bracketology by Jonathon Warriner
Updated February 11th, 2021
| South Region | West Region |
| 1.Baylor | 1.Gonzaga |
| 16.Navy/ North Carolina A&T | 16.Texas Southern/ South Dakota |
| 8.Louisville | 8.Colorado |
| 9.Florida | 9.Minnesota |
| 4.Iowa | 4.Missouri |
| 13.Wright State | 13.Furman |
| 5.USC | 5.Wisconsin |
| 12.Winthrop | 12.Western Kentucky |
| 3.Houston | 3.West Virginia |
| 14.Liberty | 14.Bryant |
| 6.Purdue | 6.Creighton |
| 11.Utah State | 11.Arkansas |
| 2.Tennessee | 2.Illinois |
| 15.Grand Canyon | 15.Vermont |
| 7.Oklahoma State | 7.Clemson |
| 10.Indiana | 10.Stanford |
| East Region | Midwest Region |
| 1.Ohio State | 1.Michigan |
| 16.Coastal Carolina | 16.Weber State |
| 8.BYU | 8.North Carolina |
| 9.Colorado State | 9.Seton Hall |
| 4.Texas Tech | 4.Oklahoma |
| 13.Toledo | 13.Abilene Christian |
| 5.Florida State | 5.Virginia Tech |
| 12.Uconn/ Oregon | 12.LSU/ Loyola-Chicago |
| 3.Virginia | 3.Texas |
| 14.Belmont | 14.UC Irvine |
| 6.Kansas | 6.UCLA |
| 11.Drake | 11.VCU |
| 2.Villanova | 2.Alabama |
| 15.Siena | 15.Northeastern |
| 7.Rutgers | 7.Xavier |
| 10.Saint Bonaventure | 10.Boise State |
NIT One Seeds: San Diego State, Ole Miss, Saint Louis, Pittsburgh
The Next Five: Richmond, Memphis, Maryland, Wichita State, Georgia Tech