Bracketology by Jonathon Warriner
Updated January 27th, 2021
| West Region | South Region |
| 1.Gonzaga | 1.Baylor |
| 16.Alabama A&M/ North Dakota State | 16.Colgate/ North Carolina A&T |
| 8.Xavier | 8.Drake |
| 9.Clemson | 9.Rutgers |
| 4.Kansas | 4.Illinois |
| 13.Abilene Christian | 13.Furman |
| 5.UCLA | 5.Florida State |
| 12.Arkansas/ Loyola-Chicago | 12.Western Kentucky |
| 3.Wisconsin | 3.Ohio State |
| 14.Bryant | 14.Siena |
| 6.Oklahoma | 6.Boise State |
| 11.LSU | 11.Stanford |
| 2.Houston | 2.Alabama |
| 15.Cal State Bakersfield | 15.Vermont |
| 7.Colorado | 7.Oklahoma State |
| 10.Indiana | 10.Oregon |
| East Region | Midwest Region |
| 1.Villanova | 1.Michigan |
| 16.Eastern Washington | 16.Texas State |
| 8.Florida | 8.Louisville |
| 9.North Carolina | 9.Uconn |
| 4.Tennessee | 4.Missouri |
| 13.Toledo | 13.Liberty |
| 5.Texas Tech | 5.Creighton |
| 12.Colorado State/ Saint Bonaventure | 12.Winthrop |
| 3.West Virginia | 3.Virginia |
| 14.Belmont | 14.Wright State |
| 6.Minnesota | 6.Purdue |
| 11.Seton Hall | 11.Saint Louis |
| 2.Iowa | 2.Texas |
| 15.Grand Canyon | 15.Northeastern |
| 7.USC | 7.BYU |
| 10.Virginia Tech | 10.Maryland |
NIT One Seeds: Syracuse, San Diego State, Richmond, Pittsburgh
The Next Five: Providence, Wichita State, VCU, Marquette, Michigan State