Bracketology by Jonathon Warriner
Updated March 13th, 2022
| West Region (San Francisco) | South Region (San Antonio) |
| 1.Gonzaga (Portland) | 1.Arizona (San Diego) |
| 16.Texas Southern/ Texas A&M CC | 16.Cal State Fullerton |
| 8.San Diego State | 8.Ohio State |
| 9.TCU | 9.Marquette |
| 4.Arkansas (Buffalo) | 4.Providence (Portland) |
| 13.Princeton | 13.New Mexico State |
| 5.Iowa | 5.St. Mary’s |
| 12.South Dakota State | 12.Indiana/ Texas A&M |
| 3.UCLA (San Diego) | 3.Texas Tech (Milwaukee) |
| 14.Montana State | 14.Delaware |
| 6.Texas | 6.LSU |
| 11.Wyoming | 11.Michigan |
| 2.Villanova (Pittsburgh) | 2.Auburn (Greenville) |
| 15.St. Peter’s | 15.Georgia State |
| 7.Boise State | 7.Colorado State |
| 10.Virginia Tech | 10.Loyola-Chicago |
| East Region (Philadelphia) | Midwest Region (Chicago) |
| 1.Baylor (Fort Worth) | 1.Kansas (Fort Worth) |
| 16.Norfolk State | 16.Wright State/ Bryant |
| 8.North Carolina | 8.Seton Hall |
| 9.Creighton | 9.Memphis |
| 4.Illinois (Pittsburgh) | 4.Wisconsin (Buffalo) |
| 13.Chattanooga | 13.Vermont |
| 5.UConn | 5.Houston |
| 12.UAB | 12.Oklahoma/ SMU |
| 3.Duke (Greenville) | 3.Purdue (Milwaukee) |
| 14.Longwood | 14.Akron |
| 6.Michigan State | 6.Alabama |
| 11.Davidson | 11.Miami |
| 2.Kentucky (Indianapolis) | 2.Tennessee (Indianapolis) |
| 15.Colgate | 15.Jacksonville State |
| 7.Murray State | 7.USC |
| 10.Iowa State | 10.San Francisco |
NIT One Seeds: Xavier, Notre Dame, Rutgers, VCU