Bracketology by Jonathon Warriner
Updated March 12th, 2022
| West Region (San Francisco) | South Region (San Antonio) |
| 1.Gonzaga (Portland) | 1.Arizona (San Diego) |
| 16.Texas Southern/ Southeast Louisiana | 16.Long Beach State/ Bryant |
| 8.San Diego State | 8.Boise State |
| 9.TCU | 9.Creighton |
| 4.UCLA (San Diego) | 4.Arkansas (Portland) |
| 13.New Mexico State | 13.Princeton |
| 5.Iowa | 5.St. Mary’s |
| 12.SMU/ Xavier | 12.South Dakota State |
| 3.Tennessee (Pittsburgh) | 3.Illinois (Milwaukee) |
| 14.Colgate | 14.Montana State |
| 6.Texas | 6.Colorado State |
| 11.Indiana | 11.Memphis |
| 2.Villanova (Pittsburgh) | 2.Baylor (Fort Worth) |
| 15.St. Peter’s | 15.Jacksonville State |
| 7.Ohio State | 7.Alabama |
| 10.Loyola-Chicago | 10.San Francisco |
| East Region (Philadelphia) | Midwest Region (Chicago) |
| 1.Kentucky (Indianapolis) | 1.Kansas (Fort Worth) |
| 16.Georgia State | 16.Wright State/ Bryant |
| 8.Seton Hall | 8.North Carolina |
| 9.Iowa State | 9.Marquette |
| 4.Wisconsin (Buffalo) | 4.Providence (Buffalo) |
| 13.Vermont | 13.Chattanooga |
| 5.UConn | 5.Houston |
| 12.Virginia Tech/ Oklahoma | 12.UAB |
| 3.Texas Tech (Milwaukee) | 3.Purdue (Indianapolis) |
| 14.Longwood | 14.Kent State |
| 6.USC | 6.LSU |
| 11.Michigan | 11.Wyoming |
| 2.Duke (Greenville) | 2.Auburn (Greenville) |
| 15.Delaware | 15.Norfolk State |
| 7.Michigan State | 7.Murray State |
| 10.Davidson | 10.Miami |
NIT One Seeds: VCU, Notre Dame, Texas A&M, Wake Forest
Others in Consideration: Rutgers, BYU