Bracketology by Jonathon Warriner
Updated February 8th, 2022
| South Region (San Antonio) | West Region (San Francisco) |
| 1.Auburn (Greenville) | 1.Gonzaga (Portland) |
| 16.Appalachain State/ Longwood | 16.Hawaii |
| 8.Seton Hall | 8.Colorado State |
| 9.Indiana | 9.TCU |
| 4.Illinois (Pittsburgh) | 4.Marquette (Buffalo) |
| 13.Chattanooga | 13.Toledo |
| 5.UCLA | 5.Ohio State |
| 12.UAB | 12.Iona |
| 3.Texas Tech (Milwaukee) | 3.Wisconsin (Milwaukee) |
| 14.Oakland | 14.Princeton |
| 6.USC | 6.Xavier |
| 11.Loyola-Chicago | 11.Miami |
| 2.Baylor (Fort Worth) | 2.Arizona (San Diego) |
| 15.Norfolk State | 15.Weber State |
| 7.St. Mary’s | 7.Boise State |
| 10.Arkansas | 10.Wake Forest |
| East Region (Philadelphia) | Midwest Region (Philadelphia) |
| 1.Kentucky (Indianapolis) | 1.Purdue (Indianapolis) |
| 16.Southern/ New Orleans | 16.Navy |
| 8.Murray State | 8.Iowa State |
| 9.San Francisco | 9.Davidson |
| 4.Houston (San Diego) | 4.Tennessee (Portland) |
| 13.South Dakota State | 13.New Mexico State |
| 5.Michigan State | 5.Texas |
| 12.Creighton/ Saint Louis | 12.Belmont/ San Diego State |
| 3.Villanova (Pittsburgh) | 3.Providence (Buffalo) |
| 14.Wagner | 14.Vermont |
| 6.Wyoming | 6.LSU |
| 11.Oregon | 11.Notre Dame |
| 2.Duke (Greenville) | 2.Kansas (Fort Worth) |
| 15.Jacksonville State | 15.UNC Greensboro |
| 7.UConn | 7.Alabama |
| 10.BYU | 10.Iowa |
NIT One Seeds: Mississippi State, Florida, North Carolina, Kansas State
The Next Five: Oklahoma, Stanford, Washington State, Utah State, Virginia